Determination of Glutamic Acid Decarboxylase (GAD65) in Pancreatic Islets and Its In Vitro and In Vivo Degradation Kinetics in Serum Using a Highly Sensitive Enzyme Immunoassay

Glutamic acid decarboxylase GAD65 autoantibodies (GADA) are an established marker for autoimmune diabetes. Recently, the autoantigen GAD65 itself was proposed as biomarker of beta-cell loss for prediction of autoimmune diabetes and graft rejection after islet transplantation. Therefore, the GAD65 co...

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Bibliographic Details
Main Authors: Michael Schlosser, Uwe Walschus, Ingrid Klöting, Reinhard Walther
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2008/961421