GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure

Autoantibodies to the γ-aminobutyric acid receptor, subtype B (GABAB), are a known cause of limbic encephalitis. The spectrum of clinical manifestations attributable to this antibody is not well defined at the present time. Here we present a case of GABAB encephalitis presenting with encephalopathy,...

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Main Authors: Matthew C. Loftspring, Eric Landsness, Lindsey Wooliscroft, Robert Rudock, Sally Jo, Kevin R. Patel
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2015/812035
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spelling doaj-9835245b8980440e8eb3fe9403669cd42020-11-24T23:24:35ZengHindawi LimitedCase Reports in Neurological Medicine2090-66682090-66762015-01-01201510.1155/2015/812035812035GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart FailureMatthew C. Loftspring0Eric Landsness1Lindsey Wooliscroft2Robert Rudock3Sally Jo4Kevin R. Patel5Department of Neurology, Washington University, St. Louis, MO 63110, USADepartment of Neurology, Washington University, St. Louis, MO 63110, USADepartment of Neurology, Washington University, St. Louis, MO 63110, USADepartment of Neurology, Washington University, St. Louis, MO 63110, USADepartment of Neurology, Washington University, St. Louis, MO 63110, USADepartment of Neurology, Washington University, St. Louis, MO 63110, USAAutoantibodies to the γ-aminobutyric acid receptor, subtype B (GABAB), are a known cause of limbic encephalitis. The spectrum of clinical manifestations attributable to this antibody is not well defined at the present time. Here we present a case of GABAB encephalitis presenting with encephalopathy, status epilepticus, dysautonomia, and acute heart failure. To our knowledge, heart failure and dysautonomia have not yet been reported with this syndrome.http://dx.doi.org/10.1155/2015/812035
collection DOAJ
language English
format Article
sources DOAJ
author Matthew C. Loftspring
Eric Landsness
Lindsey Wooliscroft
Robert Rudock
Sally Jo
Kevin R. Patel
spellingShingle Matthew C. Loftspring
Eric Landsness
Lindsey Wooliscroft
Robert Rudock
Sally Jo
Kevin R. Patel
GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
Case Reports in Neurological Medicine
author_facet Matthew C. Loftspring
Eric Landsness
Lindsey Wooliscroft
Robert Rudock
Sally Jo
Kevin R. Patel
author_sort Matthew C. Loftspring
title GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_short GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_full GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_fullStr GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_full_unstemmed GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_sort gabab encephalitis: a fifty-two-year-old man with seizures, dysautonomia, and acute heart failure
publisher Hindawi Limited
series Case Reports in Neurological Medicine
issn 2090-6668
2090-6676
publishDate 2015-01-01
description Autoantibodies to the γ-aminobutyric acid receptor, subtype B (GABAB), are a known cause of limbic encephalitis. The spectrum of clinical manifestations attributable to this antibody is not well defined at the present time. Here we present a case of GABAB encephalitis presenting with encephalopathy, status epilepticus, dysautonomia, and acute heart failure. To our knowledge, heart failure and dysautonomia have not yet been reported with this syndrome.
url http://dx.doi.org/10.1155/2015/812035
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