Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus
The WalKR signal transduction system is involved in extracellular signal recognition, but the details of this function are not well established. Here, the authors report the crystal structure of this two-component system alongside the characterisation of a small-molecule activator.
Bibliographic Details
| Main Authors: |
Quanjiang Ji,
Peter J. Chen,
Guangrong Qin,
Xin Deng,
Ziyang Hao,
Zdzislaw Wawrzak,
Won-Sik Yeo,
Jenny Winjing Quang,
Hoonsik Cho,
Guan-Zheng Luo,
Xiaocheng Weng,
Qiancheng You,
Chi-Hao Luan,
Xiaojing Yang,
Taeok Bae,
Kunqian Yu,
Hualiang Jiang,
Chuan He |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2016-03-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/ncomms11000
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