3D Printed Reconfigurable Modular Microfluidic System for Generating Gel Microspheres

3D Printed Reconfigurable Modular Microfluidic System for Generating Gel Microspheres

Integrated microfluidic systems afford extensive benefits for chemical and biological fields, yet traditional, monolithic methods of microfabrication restrict the design and assembly of truly complex systems. Here, a simple, reconfigurable and high fluid pressure modular microfluidic system is prese...

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Bibliographic Details
Main Authors: Xiaojun Chen, Deyun Mo, Manfeng Gong
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Micromachines
Subjects:
modular microfluidic system
3d printing
gel microspheres
Online Access:https://www.mdpi.com/2072-666X/11/2/224
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spelling doaj-980cd0ce87ca4fbd872bfb732879a8072020-11-25T02:51:11ZengMDPI AGMicromachines2072-666X2020-02-0111222410.3390/mi11020224mi110202243D Printed Reconfigurable Modular Microfluidic System for Generating Gel MicrospheresXiaojun Chen0Deyun Mo1Manfeng Gong2School of Mechanical and Electronic Engineering, Lingnan normal university, Zhanjiang 524048, ChinaSchool of Mechanical and Electronic Engineering, Lingnan normal university, Zhanjiang 524048, ChinaSchool of Mechanical and Electronic Engineering, Lingnan normal university, Zhanjiang 524048, ChinaIntegrated microfluidic systems afford extensive benefits for chemical and biological fields, yet traditional, monolithic methods of microfabrication restrict the design and assembly of truly complex systems. Here, a simple, reconfigurable and high fluid pressure modular microfluidic system is presented. The screw interconnects reversibly assemble each individual microfluidic module together. Screw connector provided leak-free fluidic communication, which could withstand fluid resistances up to 500 kPa between two interconnected microfluidic modules. A sample library of standardized components and connectors manufactured using 3D printing was developed. The capability for modular microfluidic system was demonstrated by generating sodium alginate gel microspheres. This 3D printed modular microfluidic system makes it possible to meet the needs of the end-user, and can be applied to bioassays, material synthesis, and other applications.https://www.mdpi.com/2072-666X/11/2/224modular microfluidic system3d printinggel microspheres
collection DOAJ
language English
format Article
sources DOAJ
author Xiaojun Chen
Deyun Mo
Manfeng Gong
spellingShingle Xiaojun Chen
Deyun Mo
Manfeng Gong
3D Printed Reconfigurable Modular Microfluidic System for Generating Gel Microspheres
Micromachines
modular microfluidic system
3d printing
gel microspheres
author_facet Xiaojun Chen
Deyun Mo
Manfeng Gong
author_sort Xiaojun Chen
title 3D Printed Reconfigurable Modular Microfluidic System for Generating Gel Microspheres
title_short 3D Printed Reconfigurable Modular Microfluidic System for Generating Gel Microspheres
title_full 3D Printed Reconfigurable Modular Microfluidic System for Generating Gel Microspheres
title_fullStr 3D Printed Reconfigurable Modular Microfluidic System for Generating Gel Microspheres
title_full_unstemmed 3D Printed Reconfigurable Modular Microfluidic System for Generating Gel Microspheres
title_sort 3d printed reconfigurable modular microfluidic system for generating gel microspheres
publisher MDPI AG
series Micromachines
issn 2072-666X
publishDate 2020-02-01
description Integrated microfluidic systems afford extensive benefits for chemical and biological fields, yet traditional, monolithic methods of microfabrication restrict the design and assembly of truly complex systems. Here, a simple, reconfigurable and high fluid pressure modular microfluidic system is presented. The screw interconnects reversibly assemble each individual microfluidic module together. Screw connector provided leak-free fluidic communication, which could withstand fluid resistances up to 500 kPa between two interconnected microfluidic modules. A sample library of standardized components and connectors manufactured using 3D printing was developed. The capability for modular microfluidic system was demonstrated by generating sodium alginate gel microspheres. This 3D printed modular microfluidic system makes it possible to meet the needs of the end-user, and can be applied to bioassays, material synthesis, and other applications.
topic modular microfluidic system
3d printing
gel microspheres
url https://www.mdpi.com/2072-666X/11/2/224
work_keys_str_mv AT xiaojunchen 3dprintedreconfigurablemodularmicrofluidicsystemforgeneratinggelmicrospheres
AT deyunmo 3dprintedreconfigurablemodularmicrofluidicsystemforgeneratinggelmicrospheres
AT manfenggong 3dprintedreconfigurablemodularmicrofluidicsystemforgeneratinggelmicrospheres
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