Platelet Transcriptome Profiling in HIV and ATP-Binding Cassette Subfamily C Member 4 (ABCC4) as a Mediator of Platelet Activity

Platelet Transcriptome Profiling in HIV and ATP-Binding Cassette Subfamily C Member 4 (ABCC4) as a Mediator of Platelet Activity

An unbiased platelet transcriptome profile identified ATP binding cassette subfamily C member 4 (ABCC4) as a novel mediator of platelet activity in virologically suppressed human immunodeficiency virus (HIV)-infected subjects on antiretroviral therapy. Using ex vivo and in vitro cellular and molecul...

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Bibliographic Details
Main Authors: Emanuela Marcantoni, PhD, Nicole Allen, BS, Matthew R. Cambria, BA, Rebecca Dann, BS, Michael Cammer, BS, Tenzin Lhakhang, BS, Meagan P. O’Brien, MD, Benjamin Kim, BS, Tilla Worgall, MD, PhD, Adriana Heguy, PhD, Aristotelis Tsirigos, PhD, Jeffrey S. Berger, MD, MS
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:JACC: Basic to Translational Science
Subjects:
ABCC4
cardiovascular disease
HIV
platelet activity
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X17302796

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