Hit-and-run programming of therapeutic cytoreagents using mRNA nanocarriers
Current widely used viral and electroporation methods for creating therapeutic cell-based products are complex and expensive. Here, the authors develop targeted mRNA nanocarriers that can transiently program gene expression by simply mixing them with cells, to improve their therapeutic potential.
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-00505-8 |
Summary: | Current widely used viral and electroporation methods for creating therapeutic cell-based products are complex and expensive. Here, the authors develop targeted mRNA nanocarriers that can transiently program gene expression by simply mixing them with cells, to improve their therapeutic potential. |
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ISSN: | 2041-1723 |