Derivation of the human embryonic stem cell line RCe009-A (RC-5)

Derivation of the human embryonic stem cell line RCe009-A (RC-5)

The human embryonic stem cell line RCe009-A (RC-5) was derived from a frozen and thawed Day 2 embryo voluntarily donated as unsuitable and surplus to requirement for fertility treatment following informed consent under licence from the UK Human Fertilisation and Embryology Authority. RCe009-A carrie...

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Main Authors: P.A. De Sousa, B. Tye, K. Bruce, P. Dand, G. Russell, D.M. Collins, J. Gardner, J.M. Downie, M. Bateman, A. Courtney
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116000726
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spelling doaj-980206e0ae53444289d487cc89a1a7bf2020-11-24T22:39:11ZengElsevierStem Cell Research1873-50611876-77532016-03-0116241842210.1016/j.scr.2016.02.030Derivation of the human embryonic stem cell line RCe009-A (RC-5)P.A. De Sousa0B. Tye1K. Bruce2P. Dand3G. Russell4D.M. Collins5J. Gardner6J.M. Downie7M. Bateman8A. Courtney9Roslin Cells Limited, Nine Edinburgh Bio-Quarter, 9 Little France Road, Edinburgh EH16 4UX, UKRoslin Cells Limited, Nine Edinburgh Bio-Quarter, 9 Little France Road, Edinburgh EH16 4UX, UKRoslin Cells Limited, Nine Edinburgh Bio-Quarter, 9 Little France Road, Edinburgh EH16 4UX, UKRoslin Cells Limited, Nine Edinburgh Bio-Quarter, 9 Little France Road, Edinburgh EH16 4UX, UKRoslin Cells Limited, Nine Edinburgh Bio-Quarter, 9 Little France Road, Edinburgh EH16 4UX, UKRoslin Cells Limited, Nine Edinburgh Bio-Quarter, 9 Little France Road, Edinburgh EH16 4UX, UKRoslin Cells Limited, Nine Edinburgh Bio-Quarter, 9 Little France Road, Edinburgh EH16 4UX, UKRoslin Cells Limited, Nine Edinburgh Bio-Quarter, 9 Little France Road, Edinburgh EH16 4UX, UKRoslin Cells Limited, Nine Edinburgh Bio-Quarter, 9 Little France Road, Edinburgh EH16 4UX, UKRoslin Cells Limited, Nine Edinburgh Bio-Quarter, 9 Little France Road, Edinburgh EH16 4UX, UKThe human embryonic stem cell line RCe009-A (RC-5) was derived from a frozen and thawed Day 2 embryo voluntarily donated as unsuitable and surplus to requirement for fertility treatment following informed consent under licence from the UK Human Fertilisation and Embryology Authority. RCe009-A carries the common DF508 mutation on the cystic fibrosis trans-membrane regulator gene associated with the disease cystic fibrosis. The cell line shows normal pluripotency marker expression and differentiation to the three germ layers in vitro. It has a normal 46XX female karyotype and microsatellite PCR identity, HLA and blood group typing data are available.http://www.sciencedirect.com/science/article/pii/S1873506116000726
collection DOAJ
language English
format Article
sources DOAJ
author P.A. De Sousa
B. Tye
K. Bruce
P. Dand
G. Russell
D.M. Collins
J. Gardner
J.M. Downie
M. Bateman
A. Courtney
spellingShingle P.A. De Sousa
B. Tye
K. Bruce
P. Dand
G. Russell
D.M. Collins
J. Gardner
J.M. Downie
M. Bateman
A. Courtney
Derivation of the human embryonic stem cell line RCe009-A (RC-5)
Stem Cell Research
author_facet P.A. De Sousa
B. Tye
K. Bruce
P. Dand
G. Russell
D.M. Collins
J. Gardner
J.M. Downie
M. Bateman
A. Courtney
author_sort P.A. De Sousa
title Derivation of the human embryonic stem cell line RCe009-A (RC-5)
title_short Derivation of the human embryonic stem cell line RCe009-A (RC-5)
title_full Derivation of the human embryonic stem cell line RCe009-A (RC-5)
title_fullStr Derivation of the human embryonic stem cell line RCe009-A (RC-5)
title_full_unstemmed Derivation of the human embryonic stem cell line RCe009-A (RC-5)
title_sort derivation of the human embryonic stem cell line rce009-a (rc-5)
publisher Elsevier
series Stem Cell Research
issn 1873-5061
1876-7753
publishDate 2016-03-01
description The human embryonic stem cell line RCe009-A (RC-5) was derived from a frozen and thawed Day 2 embryo voluntarily donated as unsuitable and surplus to requirement for fertility treatment following informed consent under licence from the UK Human Fertilisation and Embryology Authority. RCe009-A carries the common DF508 mutation on the cystic fibrosis trans-membrane regulator gene associated with the disease cystic fibrosis. The cell line shows normal pluripotency marker expression and differentiation to the three germ layers in vitro. It has a normal 46XX female karyotype and microsatellite PCR identity, HLA and blood group typing data are available.
url http://www.sciencedirect.com/science/article/pii/S1873506116000726
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