Anti-Inflammatory Effects of Vardenafil Against Cholestatic Liver Damage in Mice: a Mechanistic Study

Anti-Inflammatory Effects of Vardenafil Against Cholestatic Liver Damage in Mice: a Mechanistic Study

Background/Aims: Phosphodiesterase-5 inhibitors have beneficial effects in multiple liver diseases possibly through the reduction of oxidative stress and inflammatory response. However, these effects have not yet been examined in cholestatic liver dysfunction. Hence, this study aimed to explore the...

Full description

Bibliographic Details
Main Authors: Dina S. El-Agamy, Hamdi H. Almaramhy, Nishat Ahmed, Bsmah Bojan, Waad D. Alrohily, Mohamed A. Elkablawy
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Lithocholic acid
Hepatotoxicity
Vardenafil
Nrf2
NLRP3 inflammasome
Online Access:https://www.karger.com/Article/FullText/489986

Internet

https://www.karger.com/Article/FullText/489986

Similar Items