One-pot synthesis of 2,4,5-tri-substituted-1H-imidazoles promoted by trichloromelamine

One-pot synthesis of 2,4,5-tri-substituted-1H-imidazoles promoted by trichloromelamine

2,4,5-Trisubstituted imidazoles have many pharmaceutical properties and can be prepared via reaction of 1, 2-diketones with aldehydes in the presence of an acidic catalyst. In this work, we have prepared 2,4,5-trisubstituted imidazoles in the presence of trichloromelamine as a source of positive chl...

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Main Authors: BiBi Fatemeh Mirjalili, Abdolhamid Bamoniri, Najmeh Mohaghegh
Format: Article
Language:English
Published: Growing Science 2013-01-01
Series:Current Chemistry Letters
Subjects:
2
4
5-Trisubstituted Imidazoles
1
2-Diketones
Trichloromelamine
Aldehydes
Positive chlorine
Online Access:http://www.growingscience.com/ccl/Vol2/ccl_2012_28.pdf
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spelling doaj-97eea219bb1d40cca328655a80b967c62020-11-24T22:57:33ZengGrowing ScienceCurrent Chemistry Letters1927-72961927-730X2013-01-01213542One-pot synthesis of 2,4,5-tri-substituted-1H-imidazoles promoted by trichloromelamineBiBi Fatemeh MirjaliliAbdolhamid BamoniriNajmeh Mohaghegh2,4,5-Trisubstituted imidazoles have many pharmaceutical properties and can be prepared via reaction of 1, 2-diketones with aldehydes in the presence of an acidic catalyst. In this work, we have prepared 2,4,5-trisubstituted imidazoles in the presence of trichloromelamine as a source of positive chlorine. Short reaction times, high yield, simplicity of operation and easy work-up are some advantages of this method.http://www.growingscience.com/ccl/Vol2/ccl_2012_28.pdf245-Trisubstituted Imidazoles12-DiketonesTrichloromelamineAldehydesPositive chlorine
collection DOAJ
language English
format Article
sources DOAJ
author BiBi Fatemeh Mirjalili
Abdolhamid Bamoniri
Najmeh Mohaghegh
spellingShingle BiBi Fatemeh Mirjalili
Abdolhamid Bamoniri
Najmeh Mohaghegh
One-pot synthesis of 2,4,5-tri-substituted-1H-imidazoles promoted by trichloromelamine
Current Chemistry Letters
2
4
5-Trisubstituted Imidazoles
1
2-Diketones
Trichloromelamine
Aldehydes
Positive chlorine
author_facet BiBi Fatemeh Mirjalili
Abdolhamid Bamoniri
Najmeh Mohaghegh
author_sort BiBi Fatemeh Mirjalili
title One-pot synthesis of 2,4,5-tri-substituted-1H-imidazoles promoted by trichloromelamine
title_short One-pot synthesis of 2,4,5-tri-substituted-1H-imidazoles promoted by trichloromelamine
title_full One-pot synthesis of 2,4,5-tri-substituted-1H-imidazoles promoted by trichloromelamine
title_fullStr One-pot synthesis of 2,4,5-tri-substituted-1H-imidazoles promoted by trichloromelamine
title_full_unstemmed One-pot synthesis of 2,4,5-tri-substituted-1H-imidazoles promoted by trichloromelamine
title_sort one-pot synthesis of 2,4,5-tri-substituted-1h-imidazoles promoted by trichloromelamine
publisher Growing Science
series Current Chemistry Letters
issn 1927-7296
1927-730X
publishDate 2013-01-01
description 2,4,5-Trisubstituted imidazoles have many pharmaceutical properties and can be prepared via reaction of 1, 2-diketones with aldehydes in the presence of an acidic catalyst. In this work, we have prepared 2,4,5-trisubstituted imidazoles in the presence of trichloromelamine as a source of positive chlorine. Short reaction times, high yield, simplicity of operation and easy work-up are some advantages of this method.
topic 2
4
5-Trisubstituted Imidazoles
1
2-Diketones
Trichloromelamine
Aldehydes
Positive chlorine
url http://www.growingscience.com/ccl/Vol2/ccl_2012_28.pdf
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AT abdolhamidbamoniri onepotsynthesisof245trisubstituted1himidazolespromotedbytrichloromelamine
AT najmehmohaghegh onepotsynthesisof245trisubstituted1himidazolespromotedbytrichloromelamine
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