CpG-adjuvanted stable prefusion SARS-CoV-2 spike protein protected hamsters from SARS-CoV-2 challenge

CpG-adjuvanted stable prefusion SARS-CoV-2 spike protein protected hamsters from SARS-CoV-2 challenge

Abstract The COVID-19 pandemic presents an unprecedented challenge to global public health. Rapid development and deployment of safe and effective vaccines are imperative to control the pandemic. In the current study, we applied our adjuvanted stable prefusion SARS-CoV-2 spike (S-2P)-based vaccine,...

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Bibliographic Details
Main Authors: Chia-En Lien, Yi-Jiun Lin, Charles Chen, Wei-Cheng Lian, Tsun-Yung Kuo, John D. Campbell, Paula Traquina, Meei-Yun Lin, Luke Tzu-Chi Liu, Ya-Shan Chuang, Hui-Ying Ko, Chun-Che Liao, Yen-Hui Chen, Jia-Tsrong Jan, Hsiu-Hua Ma, Cheng-Pu Sun, Yin-Shiou Lin, Ping-Yi Wu, Yu-Chiuan Wang, Mi-Hua Tao, Yi-Ling Lin
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88283-8

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