Multitarget Anticancer Agents Based on Histone Deacetylase and Protein Kinase CK2 inhibitors

Multitarget Anticancer Agents Based on Histone Deacetylase and Protein Kinase CK2 inhibitors

The design of multitarget drugs (MTDs) has become an innovative approach for the search of effective treatments in complex diseases such as cancer. In this work, we communicate our efforts in the design of multi-targeting histone deacetylase (HDAC) and protein kinase CK2 inhibitors as a novel therap...

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Bibliographic Details
Main Authors: Regina Martínez, Bruno Di Geronimo, Miryam Pastor, José María Zapico, Claire Coderch, Rostyslav Panchuk, Nadia Skorokhyd, Maciej Maslyk, Ana Ramos, Beatriz de Pascual-Teresa
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Molecules
Subjects:
hdac
ck2
multi-target inhibitors
docking
molecular dynamics
cuaac
cytotoxic activity
Online Access:https://www.mdpi.com/1420-3049/25/7/1497

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