Microglial responses to CSF1 overexpression do not promote the expansion of other glial lineages

Microglial responses to CSF1 overexpression do not promote the expansion of other glial lineages

Abstract Background Colony-stimulating factor 1 (CSF1) expression in the central nervous system (CNS) increases in response to a variety of stimuli, and CSF1 is overexpressed in many CNS diseases. In young adult mice, we previously showed that CSF1 overexpression in the CNS caused the proliferation...

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Bibliographic Details
Main Authors: Ishani De, Vilena Maklakova, Suzanne Litscher, Michelle M. Boyd, Lucas C. Klemm, Ziyue Wang, Christina Kendziorski, Lara S. Collier
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Journal of Neuroinflammation
Subjects:
CSF1
Microglia
Astrogliosis
Oligodendrogenesis
Online Access:https://doi.org/10.1186/s12974-021-02212-0

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