DNA damage and repair in differentiation of stem cells and cells of connective cell lineages: A trigger or a complication?

The review summarizes literature data on the role of DNA breaks and DNA repair in differentiation of pluripotent stem cells (PSC) and connective cell lineages. PSC, including embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC), are rapidly dividing cells with highly active DNA dama...

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Bibliographic Details
Main Authors: Nikolajs Sjakste, Una Riekstiņa
Format: Article
Language:English
Published: PAGEPress Publications 2021-05-01
Series:European Journal of Histochemistry
Subjects:
Online Access:https://www.ejh.it/index.php/ejh/article/view/3236