Endoplasmic Reticulum Stress and Parkinson’s Disease: The Role of HRD1 in Averting Apoptosis in Neurodegenerative Disease

Endoplasmic reticulum (ER) stress has been known to be involved in the pathogenesis of various diseases, particularly neurodegenerative disorders such as Parkinson’s disease (PD). We previously identified the human ubiquitin ligase HRD1 that is associated with protection against ER stress and its as...

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Bibliographic Details
Main Authors: Tomohiro Omura, Masayuki Kaneko, Yasunobu Okuma, Kazuo Matsubara, Yasuyuki Nomura
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2013/239854