Cyclophosphamide: An Alternative Treatment in Crohn’s Disease

Cyclophosphamide: An Alternative Treatment in Crohn’s Disease

lmmunosuppressive therapy in the form of 6-mercaptopurine has shown a 66% efficacy in severe, debilitating, highly corticosteroid dependent Crohn’s disease. Nevertheless this medication has some important side effects such as nausea, vomiting, leukopenia and pancreatitis. Two patients are presented...

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Bibliographic Details
Main Authors: Gilles Lapointe, Aubin Charbonneau
Format: Article
Language:English
Published: Hindawi Limited 1989-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1989/498156
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spelling doaj-97b5a3bf6d054fe4b0ea1e57e9709f652020-11-24T23:44:15ZengHindawi LimitedCanadian Journal of Gastroenterology0835-79001989-01-013517517810.1155/1989/498156Cyclophosphamide: An Alternative Treatment in Crohn’s DiseaseGilles Lapointe0Aubin Charbonneau1Division of Gastroenterology, Chicoutimi Hospital, Chicoutimi, Qubeéc, CanadaDivision of Gastroenterology, Chicoutimi Hospital, Chicoutimi, Qubeéc, Canadalmmunosuppressive therapy in the form of 6-mercaptopurine has shown a 66% efficacy in severe, debilitating, highly corticosteroid dependent Crohn’s disease. Nevertheless this medication has some important side effects such as nausea, vomiting, leukopenia and pancreatitis. Two patients are presented who, suffering from severe Crohn’s disease, were unable to tolerate 6-mercaptopurine but showed an amazing improvement with cyclophosphamide.http://dx.doi.org/10.1155/1989/498156
collection DOAJ
language English
format Article
sources DOAJ
author Gilles Lapointe
Aubin Charbonneau
spellingShingle Gilles Lapointe
Aubin Charbonneau
Cyclophosphamide: An Alternative Treatment in Crohn’s Disease
Canadian Journal of Gastroenterology
author_facet Gilles Lapointe
Aubin Charbonneau
author_sort Gilles Lapointe
title Cyclophosphamide: An Alternative Treatment in Crohn’s Disease
title_short Cyclophosphamide: An Alternative Treatment in Crohn’s Disease
title_full Cyclophosphamide: An Alternative Treatment in Crohn’s Disease
title_fullStr Cyclophosphamide: An Alternative Treatment in Crohn’s Disease
title_full_unstemmed Cyclophosphamide: An Alternative Treatment in Crohn’s Disease
title_sort cyclophosphamide: an alternative treatment in crohn’s disease
publisher Hindawi Limited
series Canadian Journal of Gastroenterology
issn 0835-7900
publishDate 1989-01-01
description lmmunosuppressive therapy in the form of 6-mercaptopurine has shown a 66% efficacy in severe, debilitating, highly corticosteroid dependent Crohn’s disease. Nevertheless this medication has some important side effects such as nausea, vomiting, leukopenia and pancreatitis. Two patients are presented who, suffering from severe Crohn’s disease, were unable to tolerate 6-mercaptopurine but showed an amazing improvement with cyclophosphamide.
url http://dx.doi.org/10.1155/1989/498156
work_keys_str_mv AT gilleslapointe cyclophosphamideanalternativetreatmentincrohnsdisease
AT aubincharbonneau cyclophosphamideanalternativetreatmentincrohnsdisease
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