The Epithelial to Mesenchymal Transition Related Gene Calumenin Is an Adverse Prognostic Factor of Bladder Cancer Correlated With Tumor Microenvironment Remodeling, Gene Mutation, and Ferroptosis

The Epithelial to Mesenchymal Transition Related Gene Calumenin Is an Adverse Prognostic Factor of Bladder Cancer Correlated With Tumor Microenvironment Remodeling, Gene Mutation, and Ferroptosis

The tumor microenvironment (TME) plays a critical regulatory role in bladder cancer (BLCA) progression and metastasis. Epithelial-mesenchymal transition (EMT) presents as an essential mechanism of tumor invasion and metastasis. Accumulating pieces of evidence indicated that several microenvironmenta...

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Bibliographic Details
Main Authors: YiHeng Du, WenHao Miao, Xiang Jiang, Jin Cao, Bo Wang, Yi Wang, Jiang Yu, XiZhi Wang, HaiTao Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
bladder cancer
calumenin
tumor microenvironment
immunotherapy
gene mutation
ferroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.683951/full

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