Cancer and HIV-1 Infection: Patterns of Chronic Antigen Exposure

Cancer and HIV-1 Infection: Patterns of Chronic Antigen Exposure

The main role of the human immune system is to eliminate cells presenting foreign antigens and abnormal patterns, while maintaining self-tolerance. However, when facing highly variable pathogens or antigens very similar to self-antigens, this system can fail in completely eliminating the anomalies,...

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Bibliographic Details
Main Authors: Selena Vigano, Sara Bobisse, George Coukos, Matthieu Perreau, Alexandre Harari
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
HIV infection
cancer
lymphocytes
cellular immunity
exhaustion
senescence
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01350/full

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