AMP-Activated Protein Kinase (AMPK) at the Crossroads Between CO<sub>2</sub> Retention and Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease (COPD)

AMP-Activated Protein Kinase (AMPK) at the Crossroads Between CO<sub>2</sub> Retention and Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease (COPD)

Skeletal muscle dysfunction is a major comorbidity in chronic obstructive pulmonary disease (COPD) and other pulmonary conditions. Chronic CO<sub>2</sub> retention, or hypercapnia, also occur in some of these patients. Both muscle dysfunction and hypercapnia associate with higher mortali...

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Bibliographic Details
Main Authors: Joseph Balnis, Tanner C. Korponay, Ariel Jaitovich
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
ampk
protein anabolism
protein catabolism
copd
muscle atrophy
Online Access:https://www.mdpi.com/1422-0067/21/3/955

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