Fusion protein vaccines targeting two tumor antigens generate synergistic anti-tumor effects.

Fusion protein vaccines targeting two tumor antigens generate synergistic anti-tumor effects.

INTRODUCTION: Human papillomavirus (HPV) has been consistently implicated in causing several kinds of malignancies, and two HPV oncogenes, E6 and E7, represent two potential target antigens for cancer vaccines. We developed two fusion protein vaccines, PE(ΔIII)/E6 and PE(ΔIII)/E7 by targeting these...

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Bibliographic Details
Main Authors: Wen-Fang Cheng, Ming-Cheng Chang, Wei-Zen Sun, Yu-Wei Jen, Chao-Wei Liao, Yun-Yuan Chen, Chi-An Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3772923?pdf=render

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http://europepmc.org/articles/PMC3772923?pdf=render

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