Post-weaning Exposure to High-Fat Diet Induces Kidney Lipid Accumulation and Function Impairment in Adult Rats

Post-weaning Exposure to High-Fat Diet Induces Kidney Lipid Accumulation and Function Impairment in Adult Rats

Aim: We investigated the kidney morphofunctional consequences of high-fat diet intake since post-weaning in adult rats.Main Methods: Male Wistar rats were divided into two groups: ND (normal diet; n = 10) and HD (high-fat diet; n = 10). The high-fat diet was introduced post-weaned and animals were f...

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Bibliographic Details
Main Authors: Cynthia R. Muller, Ana Paula O. Leite, Rodrigo Yokota, Renata O. Pereira, Anna Laura V. Americo, Nilberto R. F. Nascimento, Fabiana S. Evangelista, Vera Farah, Manasses C. Fonteles, Patricia Fiorino
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Nutrition
Subjects:
post-weaning
high-fat diet
kidney lipid deposition
lipotoxicity
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fnut.2019.00060/full

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