Alterations in estrogen signalling pathways upon acquisition of anthracycline resistance in breast tumor cells.

Alterations in estrogen signalling pathways upon acquisition of anthracycline resistance in breast tumor cells.

Intrinsic or acquired drug resistance is a major impediment to the successful treatment of women with breast cancer using chemotherapy. We have observed that MCF-7 breast tumor cells selected for resistance to doxorubicin or epirubicin (MCF-7DOX2 and MCF-7EPI cells, respectively) exhibited increased...

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Bibliographic Details
Main Authors: Simon Chewchuk, Baoqing Guo, Amadeo Mark Parissenti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5308870?pdf=render

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