Differential effect of phosphorylation-defective survivin on radiation response in estrogen receptor-positive and -negative breast cancer.

Differential effect of phosphorylation-defective survivin on radiation response in estrogen receptor-positive and -negative breast cancer.

Survivin is a key member of the inhibitor of apoptosis protein family, and is considered a promising therapeutic target due to its universal overexpression in cancers. Survivin is implicated in cellular radiation response through its role in apoptosis, cell division, and DNA damage response. In the...

Full description

Bibliographic Details
Main Authors:	Bisrat G Debeb, Daniel L Smith, Li Li, Richard Larson, Wei Xu, Wendy A Woodward
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4357387?pdf=render

Similar Items

Genes dysregulated to different extent or oppositely in estrogen receptor-positive and estrogen receptor-negative breast cancers.
by: Xianxiao Zhou, et al.
Published: (2013-01-01)

Outcomes of Estrogen Receptor Negative and Progesterone Receptor Positive Breast Cancer.
by: Melissa Chan, et al.
Published: (2015-01-01)

Expression of NgBR is highly associated with estrogen receptor alpha and survivin in breast cancer.
by: Bei Wang, et al.
Published: (2013-01-01)

Her2 is important to androgen receptor expression and phosphorylation in estrogen receptor negative breast cancer cells
by: Chen-Chuan Huang, et al.
Published: (2012)

Dormancy signatures and metastasis in estrogen receptor positive and negative breast cancer.
by: Ryung S Kim, et al.
Published: (2012-01-01)

Location of triple-negative breast cancers: comparison with estrogen receptor-positive breast cancers on MR imaging.
by: Won Hwa Kim, et al.
Published: (2015-01-01)

Estrogen Receptor Positive/Progesterone Receptor Negative Breast Carcinomas: A Subgroup Deserves Particular Interest
by: Zühal GÜCİN, et al.
Published: (2015-08-01)

Characterization and prognosis of estrogen receptor-positive/progesterone receptor-negative male breast cancer: a population-based study
by: Jin-Li Wei, et al.
Published: (2018-12-01)

Investigation of the role of phosphorylation of the estrogen receptor, its relevance to breast cancer and involvement in resistance to anti-estrogens
by: Constantinidou, Demetra
Published: (2004)

Tetrandrine, a Compound Common in Chinese Traditional Medicine, Preferentially Kills Breast Cancer Tumor Initiating Cells (TICs) In Vitro
by: Jessica Li, et al.
Published: (2011-05-01)

Adenosine Deaminase Activity In Estrogen Receptor Positive And Negative Human Breast Cancer Cell Lines
by: Mohammad Hashemi, et al.
Published: (2005-05-01)

Support Vector Machine classifier for estrogen receptor positive and negative early-onset breast cancer.
by: Rosanna Upstill-Goddard, et al.
Published: (2013-01-01)

Support vector machine classifier for estrogen receptor positive and negative early-onset breast cancer
by: Upstill-Goddard, Rosanna, et al.
Published: (2013)

Phosphorylation Modulates Survivin Function in Behcet’s Disease
by: Yasamin Pahlavan, et al.
Published: (2020-02-01)

Aurora A phosphorylates Survivin to regulate cytoprotection
by: Ying Ho, et al.
Published: (2011)

Profiling of gene expression regulated by 17β-estradiol and tamoxifen in estrogen receptor-positive and estrogen receptor-negative human breast cancer cell lines
by: Rangel N, et al.
Published: (2017-09-01)

The RNA binding protein HuR differentially regulates unique subsets of mRNAs in estrogen receptor negative and estrogen receptor positive breast cancer
by: Chen Jing, et al.
Published: (2010-04-01)

Estrogen-mediated upregulation of Noxa is associated with cell cycle progression in estrogen receptor-positive breast cancer cells.
by: Wensheng Liu, et al.
Published: (2011-01-01)

Investigation of the mechanisms of estrogen receptor activation by phosphorylation
by: Halliday, Amy Catherine
Published: (2009)

Placental Kisspeptins Differentially Modulate Vital Parameters of Estrogen Receptor-Positive and -Negative Breast Cancer Cells.
by: Zahra Rasoulzadeh, et al.
Published: (2016-01-01)

Mouse models of estrogen receptor-positive breast cancer
by: Shakur Mohibi, et al.
Published: (2011-01-01)

Arsenic induces functional re-expression of estrogen receptor α by demethylation of DNA in estrogen receptor-negative human breast cancer.
by: Juan Du, et al.
Published: (2012-01-01)

Decreased expression of survivin, estrogen and progesterone receptors in endometrial tissues after radiofrequency treatment of dysfunctional uterine bleeding
by: Yin Geping, et al.
Published: (2012-06-01)

Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers
by: Jen-Hwey Chiu, et al.
Published: (2017-05-01)

Estrogen receptor coregulator binding modulators (ERXs) effectively target estrogen receptor positive human breast cancers
by: Ganesh V Raj, et al.
Published: (2017-08-01)

Promoter Hypermethylation of Estrogen Receptor Alpha Gene Is Correlated to Estrogen Receptor Negativity in Iranian Patients with Sporadic Breast Cancer
by: Mohammad Taghi Akbari, et al.
Published: (2012-01-01)

Multicenter retrospective study on the use of Curebest™ 95GC Breast for estrogen receptor-positive and node-negative early breast cancer
by: Fumine Tsukamoto, et al.
Published: (2021-10-01)

Insights into the Role of Estrogen Receptor β in Triple-Negative Breast Cancer
by: Assunta Sellitto, et al.
Published: (2020-06-01)

Putative Biomarkers and Targets of Estrogen Receptor Negative Human Breast Cancer
by: Stephen W. Byers, et al.
Published: (2011-07-01)

Estrogen receptor beta participate in the regulation of metabolizm of extracellular matrix in estrogen alpha negative breast cancer.
by: Mariusz Kuźmicki, et al.
Published: (2010-01-01)

Aromatase inhibition remodels the clonal architecture of estrogen-receptor-positive breast cancers
by: Christopher A. Miller, et al.
Published: (2016-08-01)

A Role for Estrogen Receptor Phosphorylation in the Resistance to Tamoxifen
by: Renée de Leeuw, et al.
Published: (2011-01-01)

Estrogen receptor-positive primary squamous cell carcinoma of the breast
by: Abby M. Pribish, BS, et al.
Published: (2017-06-01)

Estrogen receptor positive breast cancers and their association with environmental factors
by: Mannel Sylvio, et al.
Published: (2011-05-01)

Paralemmin-1 is over-expressed in estrogen-receptor positive breast cancers
by: Turk Casey M, et al.
Published: (2012-05-01)

The impact of endogenous estrogen exposures on the characteristics and outcomes of estrogen receptor positive, early breast cancer
by: Yasmin Korzets, et al.
Published: (2021-08-01)

Targeted Next-Generation Sequencing Identifies Actionable Targets in Estrogen Receptor Positive and Estrogen Receptor Negative Endometriod Endometrial Cancer
by: Siti Syazani Suhaimi, et al.
Published: (2018-07-01)

Exploiting off-target effects of estrogen deprivation to sensitize estrogen receptor negative breast cancer to immune killing
by: Jeffrey Schlom, et al.
Published: (2021-07-01)

Schisandrol A Exhibits Estrogenic Activity via Estrogen Receptor α-Dependent Signaling Pathway in Estrogen Receptor-Positive Breast Cancer Cells
by: Dahae Lee, et al.
Published: (2021-07-01)

Impact of clinical targeted sequencing on endocrine responsiveness in estrogen receptor-positive, HER2-negative metastatic breast cancer
by: Kanako Hagio, et al.
Published: (2021-04-01)