A unique carrier for delivery of therapeutic compounds beyond the blood-brain barrier.
BACKGROUND: Therapeutic intervention in many neurological diseases is thwarted by the physical obstacle formed by the blood-brain barrier (BBB) that excludes most drugs from entering the brain from the blood. Thus, identifying efficacious modes of drug delivery to the brain remains a "holy grai...
Main Authors: | Delara Karkan, Cheryl Pfeifer, Timothy Z Vitalis, Gavin Arthur, Maki Ujiie, Qingqi Chen, Sam Tsai, Gerrasimo Koliatis, Reinhard Gabathuler, Wilfred A Jefferies |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2424243?pdf=render |
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