A unique carrier for delivery of therapeutic compounds beyond the blood-brain barrier.

A unique carrier for delivery of therapeutic compounds beyond the blood-brain barrier.

BACKGROUND: Therapeutic intervention in many neurological diseases is thwarted by the physical obstacle formed by the blood-brain barrier (BBB) that excludes most drugs from entering the brain from the blood. Thus, identifying efficacious modes of drug delivery to the brain remains a "holy grai...

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Bibliographic Details
Main Authors: Delara Karkan, Cheryl Pfeifer, Timothy Z Vitalis, Gavin Arthur, Maki Ujiie, Qingqi Chen, Sam Tsai, Gerrasimo Koliatis, Reinhard Gabathuler, Wilfred A Jefferies
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2424243?pdf=render

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http://europepmc.org/articles/PMC2424243?pdf=render

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