Three months of high-fructose feeding fails to induce excessive weight gain or leptin resistance in mice.

High-fructose diets have been implicated in obesity via impairment of leptin signaling in humans and rodents. We investigated whether fructose-induced leptin resistance in mice could be used to study the metabolic consequences of fructose consumption in humans, particularly in children and adolescen...

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Bibliographic Details
Main Authors: Erik J Tillman, Donald A Morgan, Kamal Rahmouni, Steven J Swoap
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4161399?pdf=render