Local Effects Following Single and Repeat Intra-Articular Injections of Triamcinolone Acetonide Extended-Release: Results from Three Nonclinical Toxicity Studies in Dogs

Local Effects Following Single and Repeat Intra-Articular Injections of Triamcinolone Acetonide Extended-Release: Results from Three Nonclinical Toxicity Studies in Dogs

Abstract Introduction Single intra-articular (IA) injections of poly(lactic-co-glycolic acid) (PLGA) microsphere-based triamcinolone acetonide extended-release (TA–ER; formerly FX006) demonstrated sustained, clinically relevant benefits in patients with knee osteoarthritis. The local effects of TA–E...

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Bibliographic Details
Main Authors: Neil Bodick, Toni Williamson, Vibeke Strand, Becca Senter, Scott Kelley, Rogely Boyce, Ruth Lightfoot-Dunn
Format: Article
Language:English
Published: Adis, Springer Healthcare 2018-09-01
Series:Rheumatology and Therapy
Subjects:
Biodegradable polymer drug carrier
Cartilage
Corticosteroid
Intra-articular
Microsphere
Triamcinolone acetonide extended-release
Online Access:http://link.springer.com/article/10.1007/s40744-018-0125-3

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