HMB Improves Lipid Metabolism of Bama Xiang Mini-Pigs via Modulating the Bacteroidetes-Acetic Acid-AMPKα Axis

HMB Improves Lipid Metabolism of Bama Xiang Mini-Pigs via Modulating the Bacteroidetes-Acetic Acid-AMPKα Axis

Here, we used Bama Xiang mini-pigs to explore the effects of different dietary β-hydroxy-β-methylbutyrate (HMB) levels (0, 0.13, 0.64 or 1.28%) on lipid metabolism of adipose tissue. Results showed that HMB decreased the fat percentage of pigs (linearly, P < 0.05), and the lowest value was ob...

Full description

Bibliographic Details
Main Authors:	Jie Zheng, Changbing Zheng, Bo Song, Qiuping Guo, Yinzhao Zhong, Shiyu Zhang, Lingyu Zhang, Geyan Duan, Fengna Li, Yehui Duan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-08-01
Series:	Frontiers in Microbiology
Subjects:	β-hydroxy-β-methylbutyrate lipid metabolism gut microbiota acetic acid AMPKα Bama Xiang mini-pigs
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.736997/full

Similar Items

Genomic and transcriptomic analyses reveal selection of genes for puberty in Bama Xiang pigs
by: Yang Yang, et al.
Published: (2018-11-01)

Produced β-hydroxybutyrate after β-hydroxy-β-methylbutyrate (HMB) administration may contribute HMB function in mice
by: Kazuki Ikeda, et al.
Published: (2021-09-01)

β-Hydroxy-β-methylbutyrate (HMB) supplementation in prevention and treatment of elderly sarcopenia.
by: Dominika Cieślak, et al.
Published: (2018-09-01)

Effect of HMB and 2-Ox administered during pregnancy on bone properties in primiparous and multiparous minks (Neivison vison)
by: Tomaszewska Ewa, et al.
Published: (2015-12-01)

Alterations of the Muscular Fatty Acid Composition and Serum Metabolome in Bama Xiang Mini-Pigs Exposed to Dietary Beta-Hydroxy Beta-Methyl Butyrate
by: Changbing Zheng, et al.
Published: (2021-04-01)

β-Hydroxy-β-Methylbutyrate (HMB) Supplementation Prevents Bone Loss during Pregnancy—Novel Evidence from a Spiny Mouse (<i>Acomys cahirinus</i>) Model
by: Ewa Tomaszewska, et al.
Published: (2021-03-01)

The influence of dietary supplementation with the leucine metabolite β-hydroxy-β-methylbutyrate (HMB) on the chemotaxis, phagocytosis and respiratory burst of peripheral blood granulocytes and monocytes in calves
by: Roman Wójcik, et al.
Published: (2020-06-01)

β-Hydroxy β-methylbutyrate (HMB) supplementation during pregnancy and perinatal period in animals studies and possible application in humans
by: Dominika Cieślak, et al.
Published: (2018-02-01)

Effects of combined maternal administration with alpha-ketoglutarate (AKG) and <it>β</it>-hydroxy-<it>β</it>-methylbutyrate (HMB) on prenatal programming of skeletal properties in the offspring
by: Tatara Marcin R, et al.
Published: (2012-05-01)

Fourier Transform Infrared Microspectroscopy Combined with Principal Component Analysis and Artificial Neural Networks for the Study of the Effect of β-Hydroxy-β-Methylbutyrate (HMB) Supplementation on Articular Cartilage
by: Izabela Świetlicka, et al.
Published: (2021-08-01)

Non-targeted Metabolomics Reveals Metabolic Characteristics of Porcine Atretic Follicles
by: Jiayuan Mo, et al.
Published: (2021-07-01)

Transcriptional Differences of Coding and Non-Coding Genes Related to the Absence of Melanocyte in Skins of Bama Pig
by: Long Jin, et al.
Published: (2019-12-01)

The Effect of a 12-Week Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation on Highly-Trained Combat Sports Athletes: A Randomised, Double-Blind, Placebo-Controlled Crossover Study
by: Krzysztof Durkalec-Michalski, et al.
Published: (2017-07-01)

Dominansi dan Diversitas Lamun dan Makrozoobenthos pada Musim Pancaroba di Pantai Bama, Taman Nasional Baluran, Situbondo <br><i>[Dominance and Diversity of Seagrass and Macrozoobenthos on Transition Season in Bama Beach, Baluran National Park, Situbondo]<i>
by: Sapto Andriyono, et al.
Published: (2016-04-01)

Establishment of a model of Mycoplasma hyopneumoniae infection using Bama miniature pigs
by: Yuan Gan, et al.
Published: (2020-08-01)

Study on the habitat preference of Diadema setosum in Bama Coast Baluran National Park
by: Clara Puspita, et al.
Published: (2013-10-01)

The Eight Views: from its origin in the Xiao and Xiang Rivers to Hiroshige.
by: Baker, Jennifer Helen
Published: (2010)

β-hydroxy-β-methyl butyrate, but not α-ketoisocaproate and excess leucine, stimulates skeletal muscle protein metabolism in growing pigs fed low-protein diets
by: Yehui Duan, et al.
Published: (2019-01-01)

Sarcopenia in the elderly: from clinical aspects to therapeutic options
by: Angelo Bianchetti, et al.
Published: (2019-04-01)

Vegetation and Community Structure of Mangrove in Bama Resort Baluran National Park Situbondo East Java
by: Sucipto Hariyanto, et al.
Published: (2019-04-01)

The profile of Bama Beach based on the substrate the presence of seagrass coral lifeform and Echinodermata
by: Noorafebrianie Minarputri, et al.
Published: (2013-03-01)

Experimental infection of Bama miniature pigs with a highly virulent classical swine fever virus
by: Zhang Zhuo, et al.
Published: (2011-09-01)

The Effects of Prenatal Supplementation with β-Hydroxy-β-Methylbutyrate and/or Alpha-Ketoglutaric Acid on the Development and Maturation of Mink Intestines Are Dependent on the Number of Pregnancies and the Sex of the Offspring
by: Piotr Dobrowolski, et al.
Published: (2021-05-01)

Glutamin ve β-hidroksi β-metil bütiratin metotreksatin indüklediği intestinal mukozit üzerine etkisi
by: Mehmet ALAKAYA, et al.
Published: (2020-03-01)

Dietary Betaine Addition Alters Carcass Traits, Meat Quality, and Nitrogen Metabolism of Bama Mini-Pigs
by: Yating Cheng, et al.
Published: (2021-08-01)

Effect of Soyabean Isoflavones Exposure on Onset of Puberty, Serum Hormone Concentration and Gene Expression in Hypothalamus, Pituitary Gland and Ovary of Female Bama Miniature Pigs
by: Juexin Fan, et al.
Published: (2015-11-01)

Guo Xiang and the Problem of Self-Cultivation in Daoist Naturalism
by: Benjamin Coles
Published: (2019-06-01)

Pengembangan Aplikasi Manajemen Turnamen XiangQi Sistem Knockout dan Round Robin PEXI Jambi
by: Cynthia Navela Sari, et al.
Published: (2019-08-01)

Naoxintong Capsule Inhibits the Development of Cardiovascular Pathological Changes in Bama Minipig Through Improving Gut Microbiota
by: Wei-jian Zhang, et al.
Published: (2019-10-01)

Differences in gene expression and variable splicing events of ovaries between large and small litter size in Chinese Xiang pigs
by: Xueqin Ran, et al.
Published: (2021-09-01)

Assessment of M. longissimus fibre types and metabolic enzymes in Bama miniature pigs and Landrace swine
by: Baojian Chen, et al.
Published: (2018-01-01)

Effects of β-hydroxy-β-methylbutyrate supplementation on muscle mass and strength in onabotulinumtoxin type-A-injected and contralateral quadriceps femoris in rabbits
by: Rafael Fortuna, et al.
Published: (2021-09-01)

A Proton-Coupled Transport System for β-Hydroxy-β-Methylbutyrate (HMB) in Blood–Brain Barrier Endothelial Cell Line hCMEC/D3
by: Kei Higuchi, et al.
Published: (2021-09-01)

Women on the Threshold in the First Chapter of Liu Xiang’s Lienü Zhuan: The Gendered Concepts of Nei 内/Wai 外 and the Way of Women (Fu Dao 婦道)
by: Sabrina Ardizzoni
Published: (2020-09-01)

Un monde en un mot du bouddhisme chinois : études autour du terme xiang à partir du Sūtra du diamant de Kumārajīva
by: Wang, Han-Chi
Published: (2017)

Heat Stress Upregulates the Expression of TLR4 and Its Alternative Splicing Variant in Bama Miniature Pigs
by: Xiang-hong JU, et al.
Published: (2014-11-01)

The impact of acute beta-hydroxy-beta-methylbutyrate (HMB) ingestion on glucose and insulin kinetics in young and older men
by: Philip J.J. Herrod, et al.
Published: (2020-10-01)

Adiponectin induced AMP-activated protein kinase impairment mediates insulin resistance in Bama mini-pig fed high-fat and high-sucrose diet
by: Miaomiao Niu, et al.
Published: (2017-08-01)

Identification of a Compound That Inhibits the Growth of Gram-Negative Bacteria by Blocking BamA–BamD Interaction
by: Yan Li, et al.
Published: (2020-06-01)

Longitudinal Expression of Testicular <i>TAS1R3</i> from Prepuberty to Sexual Maturity in Congjiang Xiang Pigs
by: Ting Gong, et al.
Published: (2021-02-01)