Development of Novel Oral Formulations of Disulfide Antioxidants Based on Porous Silica for Controlled Release of the Drugs

Powerful antioxidant α‑lipoic acid (LA) exhibits limited therapeutic efficiency due to its pharmacokinetic properties. Therefore, the purpose of this work was to evaluate the ability of silica‑based composites of LA as well as its amide (lipoamide, LM), as new oral drug formulations, to control thei...

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Bibliographic Details
Main Authors: Ekaterina S. Dolinina, Elena V. Parfenyuk
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/14/4/963