First case of Kluyveromyces marxianus (Candida kefyr) late onset keratitis after lamellar endothelial corneal graft

First case of Kluyveromyces marxianus (Candida kefyr) late onset keratitis after lamellar endothelial corneal graft

We present a case of Kluyveromyces marxianus keratitis nine months after Descemet's membrane endothelial keratoplasty (DMEK) in a patient with Fuchs endothelial disease. Endothelial scraping revealed this rare yeast infection at the interface between graft and host cornea. Immediate antifungal...

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Bibliographic Details
Main Authors: Alexander M. Aldejohann, Johanna Theuersbacher, Lukas Haug, Olga S. Lamm, Grit Walther, Oliver Kurzai, Jost Hillenkamp, Daniel Kampik
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Medical Mycology Case Reports
Subjects:
Fungal keratits
Kluyveromyces marxianus (Candida kefyr)
DMEK
Corneal transplantation
Voriconazole
Amphotericin B
Online Access:http://www.sciencedirect.com/science/article/pii/S2211753921000051
Description
Summary:We present a case of Kluyveromyces marxianus keratitis nine months after Descemet's membrane endothelial keratoplasty (DMEK) in a patient with Fuchs endothelial disease. Endothelial scraping revealed this rare yeast infection at the interface between graft and host cornea. Immediate antifungal treatment with intracameral and corneal intrastromal injections of voriconazole and amphotericin B remained unsuccessful, requiring penetrating keratoplasty. This case highlights the challenging management of keratomycosis in patients with endothelial grafts.
ISSN:2211-7539

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