EOMES interacts with RUNX3 and BRG1 to promote innate memory cell formation through epigenetic reprogramming
T box transcription factor Eomesodermin (EOMES) is induced when naïve T cells are converted to innate memory T cells in response to cytokines. Here the authors show that EOMES is recruited to RUNX3-bound enhancers and interacts with BRG1 during innate memory T cell formation.
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2019-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-11233-6 |