EOMES interacts with RUNX3 and BRG1 to promote innate memory cell formation through epigenetic reprogramming
T box transcription factor Eomesodermin (EOMES) is induced when naïve T cells are converted to innate memory T cells in response to cytokines. Here the authors show that EOMES is recruited to RUNX3-bound enhancers and interacts with BRG1 during innate memory T cell formation.
Bibliographic Details
| Main Authors: |
Nicolas Istaces,
Marion Splittgerber,
Viviana Lima Silva,
Muriel Nguyen,
Séverine Thomas,
Aurore Le,
Younes Achouri,
Emilie Calonne,
Matthieu Defrance,
François Fuks,
Stanislas Goriely,
Abdulkader Azouz |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2019-07-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-019-11233-6
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