Reaction mixtures formed by nitrite and selected sulfa-drugs showed mutagenicity in acidic medium

Reaction mixtures formed by nitrite and selected sulfa-drugs showed mutagenicity in acidic medium

Nitrite, which is present in preserved meat and can be produced in the oral cavity by reduction of nitrate taken from vegetables, could react in stomach with nitrosatable drugs, giving genotoxic-carcinogenic N-nitroso compounds (NOC). The mutagenicity of reaction mixtures formed by sodium nitrite an...

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Bibliographic Details
Main Authors:	Claudia Trossero, Ana Pontoriero, Estela Hure, Laura Monti, Carolina Gorr, Natalia Mosconi, Marcela Rizzotto, Graciela Caffarena
Format:	Article
Language:	English
Published:	Sociedade Brasileira de Química 2009-01-01
Series:	Química Nova
Subjects:	nitrite sulfa-drugs mutagenicity
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000500013

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