Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis

Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis

Metastasis is the leading cause of death in patients with advanced melanoma, yet the somatic alterations that aid tumour cell dissemination and colonisation are poorly understood. Here, we deploy comparative genomics to identify and validate clinically relevant drivers of melanoma metastasis. To do...

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Bibliographic Details
Main Authors: Martin Del Castillo Velasco‐Herrera, Louise van derWeyden, Jeremie Nsengimana, Anneliese O. Speak, Marcela K. Sjöberg, David Timothy Bishop, Göran Jönsson, Julia Newton‐Bishop, David J. Adams
Format: Article
Language:English
Published: Wiley 2018-02-01
Series:Molecular Oncology
Subjects:
comparative genomics
CRISPR
melanoma
RNA‐Seq
Online Access:https://doi.org/10.1002/1878-0261.12161

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