Depression in Parkinson's disease: study of 60 cases Depressão na doença de Parkinson: estudo de 60 casos

Depression is very frequent in Parkinson’s disease (PD) and largely unrecognized by neurologists, emphasizing the need of an approach to psychiatric symptoms by non psychiatrists in order to ensure an early diagnosis of depression in PD; clinical characteristics and the prevalence rate of depression...

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Bibliographic Details
Main Authors: Roberto César Pereira do Prado, Egberto Reis Barbosa
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2005-09-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2005000500009
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Summary:Depression is very frequent in Parkinson’s disease (PD) and largely unrecognized by neurologists, emphasizing the need of an approach to psychiatric symptoms by non psychiatrists in order to ensure an early diagnosis of depression in PD; clinical characteristics and the prevalence rate of depression in PD were evaluated and the relationship of depression in PD with other variables were determined. Sixty PD subjects, who fulfilled the clinical criteria for primary PD, 56,6% males, age range from 44 to 85 years old, in different stages of the disease were investigated. All subjects were submitted to the UPDRS-III, V and VI, Clinical Interview Schedule and the Hamilton depression scale. A significant correlation was found between depression and UPDRS-III, V and VI, anxiety and irritability. The frequency of depression in PD in this study was nearly 40% possessing specific features. Structured interviews and evaluation scales are essential for an accurate diagnosis and proper treatment of depression in PD.<br>A depressão é manifestação freqüente na evolução da doença de Parkinson (DP), gerando a necessidade de nova abordagem neuropsiquiátrica por parte dos médicos não psiquiatras, visando o reconhecimento precoce do quadro depressivo na DP. Foram estudadas as características clínicas e freqüência da depressão na DP e correlacionadas com outras variáveis. Sessenta pacientes que preenchiam os critérios clínicos atuais para DP, sendo 56,6% do sexo masculino (44 a 85 anos), em diferentes estágios clínicos da doença, foram submetidos ás escalas de avaliação para DP (UPDRS-III, V e VI), para transtornos neuropsiquiátricos - Entrevista Clínica Estruturada e Escala de Hamilton. Houve associação estatisticamente significante entre depressão e UPDRS-III, V e VI, ansiedade e irritabilidade. A freqüência de depressão, situou-se em torno de 40% apresentando características próprias. Entrevistas estruturadas e escalas de avaliação são essenciais para o diagnóstico preciso e tratamento adequado do fenômeno depressivo na DP.
ISSN:0004-282X
1678-4227