Ultrasensitive Negative Feedback Control: A Natural Approach for the Design of Synthetic Controllers.

Many of the most important potential applications of Synthetic Biology will require the ability to design and implement high performance feedback control systems that can accurately regulate the dynamics of multiple molecular species within the cell. Here, we argue that the use of design strategies...

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Bibliographic Details
Main Authors: Francesco Montefusco, Ozgur E Akman, Orkun S Soyer, Declan G Bates
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5004582?pdf=render