Correlation between the type of bcr-abl transcripts and blood cell counts in chronic myeloid leukemia – a possible influence of mdr1 gene expression

Correlation between the type of bcr-abl transcripts and blood cell counts in chronic myeloid leukemia – a possible influence of mdr1 gene expression

The impact of BCR-ABL mRNA type (b3a2 vs. b2a2) on chronic myeloid leukemia (CML) phenotype is still a subject of controversies. We searched for a correlation between the BCR-ABL transcripts type and CML patients’ characteristics, including MDR1 gene expression. Ninety-eight untreated chronic phase...

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Bibliographic Details
Main Authors: Gueorgui Balatzenko, Babu Rao Vundinti, Guenova Margarita
Format: Article
Language:English
Published: PAGEPress Publications 2011-03-01
Series:Hematology Reports
Subjects:
Chronic Myeloid Leukemia
BCR-ABL breakpoint
b3a2
b2a2
MDR1 gene expression
Online Access:http://www.pagepress.org/journals/index.php/hr/article/view/2244

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