miR-34a Regulates Multidrug Resistance via Positively Modulating OAZ2 Signaling in Colon Cancer Cells

miR-34a Regulates Multidrug Resistance via Positively Modulating OAZ2 Signaling in Colon Cancer Cells

Although aberrant expression of miR-34a, an essential tumor suppressor miRNA, has been frequently observed in colon cancer (CCa), whether miR-34a can regulate CCa progression by modulating other facets of this malignancy (such as multidrug resistance, MDR) remains unknown. Here, we report for the fi...

Full description

Bibliographic Details
Main Authors:	Yong Li, Ping Gong, Ji-xue Hou, Wei Huang, Xiao-ping Ma, Yu-li Wang, Jing Li, Xiao-bin Cui, Na Li
Format:	Article
Language:	English
Published:	Hindawi Limited 2018-01-01
Series:	Journal of Immunology Research
Online Access:	http://dx.doi.org/10.1155/2018/7498514

Similar Items

OAZ-t/OAZ3 is essential for rigid connection of sperm tails to heads in mouse.
by: Keizo Tokuhiro, et al.
Published: (2009-11-01)

An Aesthetic Comparison between Wang Chen-Ho and Oaz Yasujiro
by: Jia-PengLin, et al.
Published: (2010)

miR-103/miR-195/miR-15b Regulate SALL4 and Inhibit Proliferation and Migration in Glioma
by: Li-Ping Chen, et al.
Published: (2018-11-01)

Characterization of OAZ1 and its potential functions in goose follicular development
by: Bo Kang, et al.
Published: (2017-03-01)

miR-34a induces spine damages via inhibiting synaptotagmin-1 in depression
by: Li-Tao Yi, et al.
Published: (2020-11-01)

Mechanistic role of miR-24 and miR-34 in progression in myocardial infarction
by: Zhen Wang, et al.
Published: (2020-01-01)

miR-34 modulates wing polyphenism in planthopper.
by: Xinhai Ye, et al.
Published: (2019-06-01)

Methylation of <it>miR-34a, miR-34b/c</it>, <it>miR-124-1 </it>and <it>miR-203 </it>in Ph-negative myeloproliferative neoplasms
by: Chim Chor Sang, et al.
Published: (2011-11-01)

Posttranscriptional deregulation of Src due to aberrant miR34a and miR203 contributes to gastric cancer development
by: Qiang Hao, et al.
Published: (2013-06-01)

MiR-34a in Age and Tissue Related Radio-Sensitivity and Serum miR-34a as a Novel Indicator of Radiation Injury
by: Cong Liu, Chuanfeng Zhou, Fu Gao, Shengyun Cai, Chao Zhang, Luqian Zhao, Fang Zhao, Fei Cao, Jing Lin, Yanyong Yang, Jin Ni, Jun Jia, Wei Wu, Li Zhou, Jianguo Cui, Wei Zhang, Bailong Li, Jianming Cai
Published: (2011-01-01)

Quantitative proteomic analysis of gene regulation by miR-34a and miR-34c.
by: Olivia A Ebner, et al.
Published: (2014-01-01)

Clinical Significance and Prognostic Value of miR-28-5p in Colon Cancer
by: Ji-lin Li, et al.
Published: (2020-01-01)

LINC02418 promotes colon cancer progression by suppressing apoptosis via interaction with miR-34b-5p/BCL2 axis
by: Jun Tian, et al.
Published: (2020-09-01)

Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression
by: Julie Chao, et al.
Published: (2017-01-01)

miR-34 Modulates Innate Immunity and Ecdysone Signaling in Drosophila.
by: Xiao-Peng Xiong, et al.
Published: (2016-11-01)

Plasma microRNAs, miR-223, miR-21 and miR-218, as novel potential biomarkers for gastric cancer detection.
by: Bo-sheng Li, et al.
Published: (2012-01-01)

OAZ1 knockdown enhances viability and inhibits ER and LHR transcriptions of granulosa cells in geese.
by: Bo Kang, et al.
Published: (2017-01-01)

Expression and clinical significance of serum miR-23a and miR-34a in patients with age-related macular degeneration
by: Hui-Li Li, et al.
Published: (2019-01-01)

miR-26a Reverses Multidrug Resistance in Osteosarcoma by Targeting MCL1
by: Ming Li, et al.
Published: (2021-03-01)

MiR-34a and miR-34b/c have distinct effects on the suppression of lung adenocarcinomas
by: Jeong Seon Kim, et al.
Published: (2019-01-01)

Regorafenib suppresses colon tumorigenesis and the generation of drug resistant cancer stem-like cells via modulation of miR-34a associated signaling
by: Mao-Hua Cai, et al.
Published: (2018-07-01)

miR-34a is a microRNA safeguard for Citrobacter-induced inflammatory colon oncogenesis
by: Lihua Wang, et al.
Published: (2018-12-01)

lncRNA KCNQ1OT1 enhances the chemoresistance of oxaliplatin in colon cancer by targeting the miR-34a/ATG4B pathway
by: Li Y, et al.
Published: (2019-04-01)

Role of microRNA miR-34a in liver cancer stem cells
by: Lu-Lu Gong, et al.
Published: (2016-03-01)

Lack of association of MiR-34b/c polymorphism (rs4938723) with hepatocellular carcinoma: a meta-analysis.
by: Tie-Jun Liang, et al.
Published: (2013-01-01)

The Mediation of miR-34a/miR-449c for Immune Cytokines in Acute Cold/Heat-Stressed Broiler Chicken
by: Tao Li, et al.
Published: (2020-11-01)

Identification of Four Oxidative Stress-Responsive MicroRNAs, miR-34a-5p, miR-1915-3p, miR-638, and miR-150-3p, in Hepatocellular Carcinoma
by: Yong Wan, et al.
Published: (2017-01-01)

miR-34b/c rs4938723 T>C Decreases Neuroblastoma Risk: A Replication Study in the Hunan Children
by: Yong Li, et al.
Published: (2019-01-01)

Exosomes overexpressing miR-34c inhibit malignant behavior and reverse the radioresistance of nasopharyngeal carcinoma
by: Fang-Zhu Wan, et al.
Published: (2020-01-01)

Adipocyte-Derived Leptin Promotes PAI-1 -Mediated Breast Cancer Metastasis in a STAT3/miR-34a Dependent Manner
by: Si-Jing Li, et al.
Published: (2020-12-01)

Dihydromyricetin Alleviates High Glucose-Induced Oxidative Stress and Apoptosis in Human Retinal Pigment Epithelial Cells by Downregulating miR-34a Expression
by: Li W, et al.
Published: (2021-01-01)

HIF-1α Induces Multidrug Resistance in Gastric Cancer Cells by Inducing MiR-27a.
by: Qun Zhao, et al.
Published: (2015-01-01)

The Role of miR-34a in Tritiated Water Toxicity in Human Umbilical Vein Endothelial Cells
by: Feng Mei Cui, et al.
Published: (2016-03-01)

The DNMT1/miR-34a Axis Is Involved in the Stemness of Human Osteosarcoma Cells and Derived Stem-Like Cells
by: Xiao Liang, et al.
Published: (2019-01-01)

miR-34b inhibits nasopharyngeal carcinoma cell proliferation by targeting ubiquitin-specific peptidase 22
by: Xiao J, et al.
Published: (2016-03-01)

The p53/miR-34a/SIRT1 Positive Feedback Loop in Quercetin-Induced Apoptosis
by: Guohua Lou, et al.
Published: (2015-04-01)

Exosome and Melatonin Additively Attenuates Inflammation by Transferring miR-34a, miR-124, and miR-135b
by: June Seok Heo, et al.
Published: (2020-01-01)

Expressions of miR-96 and miR-103 in Hepatocellular Carcinoma and Their Correlation with Prognosis
by: XIAO Wei, et al.
Published: (2020-06-01)

Deoxyelephantopin Induces Apoptosis and Enhances Chemosensitivity of Colon Cancer via miR-205/Bcl2 Axis
by: Cui, H., et al.
Published: (2022)

Regulation of c-Myc by miR-34c
by: Cannell, Ian G.
Published: (2009)