Liquid Biopsy Detects Relapse Five Months Earlier than Regular Clinical Follow-Up and Guides Targeted Treatment in Breast Cancer

Genetic alterations in circulating tumor DNA (ctDNA) are an emerging biomarker for the early detection of relapse and have the potential to guide targeted treatment. ctDNA analysis is often performed by droplet digital PCR; however, next-generation sequencing (NGS) allows multigene testing without h...

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Bibliographic Details
Main Authors: Fiona Tsui-Fen Cheng, Nina Lapke, Chin-Chu Wu, Yen-Jung Lu, Shu-Jen Chen, Pei-Ning Yu, Yen-Ting Liu, Kien Thiam Tan
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2019/6545298

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