Nicotinamide impairs entry into and exit from meiosis I in mouse oocytes.

Nicotinamide impairs entry into and exit from meiosis I in mouse oocytes.

Following exit from meiosis I, mammalian oocytes immediately enter meiosis II without an intervening interphase, accompanied by rapid reassembly of a bipolar spindle that maintains condensed chromosomes in a metaphase configuration (metaphase II arrest). Here we study the effect of nicotinamide (NAM...

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Bibliographic Details
Main Authors: Angelique Riepsamen, Lindsay Wu, Laurin Lau, Dave Listijono, William Ledger, David Sinclair, Hayden Homer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4418673?pdf=render

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