Multidisciplinary Care of Patients with Intrahepatic Cholangiocarcinoma: Updates in Management

Cholangiocarcinoma is a highly fatal primary cancer of the bile ducts which arises from malignant transformation of bile duct epithelium. While being an uncommon malignancy with an annual incidence in the United States of 5000 new cases, the incidence has been increasing over the past 30 years and c...

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Main Authors: Kelly J. Lafaro, David Cosgrove, Jean-Francois H. Geschwind, Ihab Kamel, Joseph M. Herman, Timothy M. Pawlik
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2015/860861
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spelling doaj-97168fd559984b4481a4cb644c160c0e2020-11-25T00:19:42ZengHindawi LimitedGastroenterology Research and Practice1687-61211687-630X2015-01-01201510.1155/2015/860861860861Multidisciplinary Care of Patients with Intrahepatic Cholangiocarcinoma: Updates in ManagementKelly J. Lafaro0David Cosgrove1Jean-Francois H. Geschwind2Ihab Kamel3Joseph M. Herman4Timothy M. Pawlik5Department of Surgery, Johns Hopkins Hospital, Baltimore, MD 21287, USADepartment of Oncology, Johns Hopkins Hospital, Baltimore, MD 21287, USADepartment of Radiology, Johns Hopkins Hospital, Baltimore, MD 21287, USADepartment of Radiology, Johns Hopkins Hospital, Baltimore, MD 21287, USADepartment of Radiation Oncology, Johns Hopkins Hospital, Baltimore, MD 21287, USADepartment of Surgery, Johns Hopkins Hospital, Baltimore, MD 21287, USACholangiocarcinoma is a highly fatal primary cancer of the bile ducts which arises from malignant transformation of bile duct epithelium. While being an uncommon malignancy with an annual incidence in the United States of 5000 new cases, the incidence has been increasing over the past 30 years and comprises 3% of all gastrointestinal cancers. Cholangiocarcinoma can be classified into intrahepatic (ICC) and extrahepatic (including hilar and distal bile duct) according to its anatomic location within the biliary tree with respect to the liver. This paper reviews the management of ICC, focusing on the epidemiology, risk factors, diagnosis, and surgical and nonsurgical management.http://dx.doi.org/10.1155/2015/860861
collection DOAJ
language English
format Article
sources DOAJ
author Kelly J. Lafaro
David Cosgrove
Jean-Francois H. Geschwind
Ihab Kamel
Joseph M. Herman
Timothy M. Pawlik
spellingShingle Kelly J. Lafaro
David Cosgrove
Jean-Francois H. Geschwind
Ihab Kamel
Joseph M. Herman
Timothy M. Pawlik
Multidisciplinary Care of Patients with Intrahepatic Cholangiocarcinoma: Updates in Management
Gastroenterology Research and Practice
author_facet Kelly J. Lafaro
David Cosgrove
Jean-Francois H. Geschwind
Ihab Kamel
Joseph M. Herman
Timothy M. Pawlik
author_sort Kelly J. Lafaro
title Multidisciplinary Care of Patients with Intrahepatic Cholangiocarcinoma: Updates in Management
title_short Multidisciplinary Care of Patients with Intrahepatic Cholangiocarcinoma: Updates in Management
title_full Multidisciplinary Care of Patients with Intrahepatic Cholangiocarcinoma: Updates in Management
title_fullStr Multidisciplinary Care of Patients with Intrahepatic Cholangiocarcinoma: Updates in Management
title_full_unstemmed Multidisciplinary Care of Patients with Intrahepatic Cholangiocarcinoma: Updates in Management
title_sort multidisciplinary care of patients with intrahepatic cholangiocarcinoma: updates in management
publisher Hindawi Limited
series Gastroenterology Research and Practice
issn 1687-6121
1687-630X
publishDate 2015-01-01
description Cholangiocarcinoma is a highly fatal primary cancer of the bile ducts which arises from malignant transformation of bile duct epithelium. While being an uncommon malignancy with an annual incidence in the United States of 5000 new cases, the incidence has been increasing over the past 30 years and comprises 3% of all gastrointestinal cancers. Cholangiocarcinoma can be classified into intrahepatic (ICC) and extrahepatic (including hilar and distal bile duct) according to its anatomic location within the biliary tree with respect to the liver. This paper reviews the management of ICC, focusing on the epidemiology, risk factors, diagnosis, and surgical and nonsurgical management.
url http://dx.doi.org/10.1155/2015/860861
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