Recent advances in methods to assess the activity of the kinome [version 1; referees: 3 approved]
Protein and lipid kinases are deregulated in most, if not all, cancers and are among the most valuable therapeutic targets in these diseases. Despite the introduction of dozens of effective kinase inhibitors into clinical practice, the development of drug resistance remains a major barrier to treatm...
Main Authors: | Maria Radu, Jonathan Chernoff |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2017-06-01
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Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/6-1004/v1 |
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