Generation of GM-CSF-producing antigen-presenting cells that induce a cytotoxic T cell-mediated antitumor response

Generation of GM-CSF-producing antigen-presenting cells that induce a cytotoxic T cell-mediated antitumor response

Immunotherapy using dendritic cells (DCs) is a promising treatment modality for cancer. However, the limited number of functional DCs from peripheral blood has been linked to the unsatisfactory clinical efficacies of current DC-based cancer immunotherapies. We previously generated proliferating anti...

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Bibliographic Details
Main Authors: Hiroaki Mashima, Rong Zhang, Tsuyoshi Kobayashi, Yuichiro Hagiya, Hirotake Tsukamoto, Tianyi Liu, Tatsuaki Iwama, Masateru Yamamoto, Chiahsuan Lin, Ryusuke Nakatsuka, Yuta Mishima, Noriko Watanabe, Takashi Yamada, Satoru Senju, Shin Kaneko, Alimjan Idiris, Tetsuya Nakatsura, Hideki Ohdan, Yasushi Uemura
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
cancer immunotherapy
cancer vaccine
dendritic cell
gm-csf
induced pluripotent stem cell
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1814620

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