Human articular chondrocytes regulate immune response by affecting directly T cell proliferation and indirectly inhibiting monocyte differentiation to professional antigen presenting cells.

Human articular chondrocytes regulate immune response by affecting directly T cell proliferation and indirectly inhibiting monocyte differentiation to professional antigen presenting cells.

Autologous Chondrocyte Implantation (ACI) is the current gold standard cell therapy for cartilage lesions. However, in some instances, the heavily compromised health of the patient can either impair or limit the recovery of the autologous chondrocytes and a satisfactory outcome of the implant. Allog...

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Bibliographic Details
Main Authors: Rui Pereira, Daniela Martinelli, Ranieri Cancedda, Chiara Gentili, Alessandro Poggi
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Immunology
Subjects:
immune response
T lymphocyte
Dentritic cells
Chondrocyte implantation
Antigen presenting cells (APC)
allogenic cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00415/full

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