Over-expression of calpastatin inhibits calpain activation and attenuates post-infarction myocardial remodeling.

Over-expression of calpastatin inhibits calpain activation and attenuates post-infarction myocardial remodeling.

Calpain is activated following myocardial infarction and ablation of calpastatin (CAST), an endogenous inhibitor of calpains, promotes left ventricular remodeling after myocardial infarction (MI). The present study aimed to investigate the effect of transgenic over-expression of CAST on the post-inf...

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Bibliographic Details
Main Authors:	Tingqiao Ye, Qiang Wang, Yan Zhang, Xiaofeng Song, Dachun Yang, De Li, Dan Li, Linan Su, Yongjian Yang, Shuangtao Ma
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4364764?pdf=render

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