Cardiorespiratory pathogenesis of sickle cell disease in a mouse model

Abstract The nature and development of cardiorespiratory impairments associated with sickle cell disease are poorly understood. Given that the mechanisms of these impairments cannot be addressed adequately in clinical studies, we characterized cardiorespiratory pathophysiology from birth to maturity...

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Bibliographic Details
Main Authors: Jun Ren, Xiuqing Ding, Marie Trudel, John J. Greer, Joanna E. MacLean
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08860-8