Direct proof of the in vivo pathogenic role of the AChR autoantibodies from myasthenia gravis patients.

Direct proof of the in vivo pathogenic role of the AChR autoantibodies from myasthenia gravis patients.

Several studies have suggested that the autoantibodies (autoAbs) against muscle acetylcholine receptor (AChR) of myasthenia gravis (MG) patients are the main pathogenic factor in MG; however, this belief has not yet been confirmed with direct observations. Although animals immunized with AChR or inj...

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Bibliographic Details
Main Authors: Gregory Kordas, George Lagoumintzis, Sotirios Sideris, Konstantinos Poulas, Socrates J Tzartos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4178151?pdf=render

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