The use of IntegraTM as a novel technique in deep burn foot management

Summary: Deep burns in patients with co-morbidities carry a significant challenge for surgeons. The use of synthetic skin substitutes has played an increasingly important role in tissue reconstruction. IntegraTM is an artificial dermal substitute that allows temporary coverage after burn excision. T...

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Main Authors: Mohammed Asif, Saarah Ebrahim, Melanie Major, Julie Caffrey
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:JPRAS Open
Online Access:http://www.sciencedirect.com/science/article/pii/S2352587818300172
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spelling doaj-96fb03321969466ca22076369ff1bb1d2020-11-24T20:52:11ZengElsevierJPRAS Open2352-58782018-09-01171520The use of IntegraTM as a novel technique in deep burn foot managementMohammed Asif0Saarah Ebrahim1Melanie Major2Julie Caffrey3Corresponding author.; Johns Hopkins Burn Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USAJohns Hopkins Burn Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USAJohns Hopkins Burn Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USAJohns Hopkins Burn Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USASummary: Deep burns in patients with co-morbidities carry a significant challenge for surgeons. The use of synthetic skin substitutes has played an increasingly important role in tissue reconstruction. IntegraTM is an artificial dermal substitute that allows temporary coverage after burn excision. The main advantages of this bi-layered template are its immediate availability, optimal scarring and decreased requirement for donor tissue. However, the downsides are the requirement for complex wound care, risk of infection and two stage procedure that can be both costly and prolong the stay in hospital. Here, we present the case of a patient with deep burns to the plantar aspect of both feet. Given the patient's medical history of diabetes, hypertension and peripheral neuropathy, we elected to use IntegraTM in combination with negative pressure wound therapy. Three weeks after the application of the IntegraTM matrix, the surface layer was replaced with autograft. At discharge, the patient was fully ambulatory and six months post-operatively this status was maintained without significant graft breakdown. To the best of our knowledge, the use of IntegraTM and split thickness skin graft in the management of full thickness burns to the plantar aspect of the feet has not been reported previously. Overall, our experience with IntegraTM in this setting was found to be satisfactory and can be considered as a promising treatment option in acute burn resurfacing. Keywords: Burns, Dermal substitute, Integra™, Negative pressure wound therapy, Skin graft, Split thicknesshttp://www.sciencedirect.com/science/article/pii/S2352587818300172
collection DOAJ
language English
format Article
sources DOAJ
author Mohammed Asif
Saarah Ebrahim
Melanie Major
Julie Caffrey
spellingShingle Mohammed Asif
Saarah Ebrahim
Melanie Major
Julie Caffrey
The use of IntegraTM as a novel technique in deep burn foot management
JPRAS Open
author_facet Mohammed Asif
Saarah Ebrahim
Melanie Major
Julie Caffrey
author_sort Mohammed Asif
title The use of IntegraTM as a novel technique in deep burn foot management
title_short The use of IntegraTM as a novel technique in deep burn foot management
title_full The use of IntegraTM as a novel technique in deep burn foot management
title_fullStr The use of IntegraTM as a novel technique in deep burn foot management
title_full_unstemmed The use of IntegraTM as a novel technique in deep burn foot management
title_sort use of integratm as a novel technique in deep burn foot management
publisher Elsevier
series JPRAS Open
issn 2352-5878
publishDate 2018-09-01
description Summary: Deep burns in patients with co-morbidities carry a significant challenge for surgeons. The use of synthetic skin substitutes has played an increasingly important role in tissue reconstruction. IntegraTM is an artificial dermal substitute that allows temporary coverage after burn excision. The main advantages of this bi-layered template are its immediate availability, optimal scarring and decreased requirement for donor tissue. However, the downsides are the requirement for complex wound care, risk of infection and two stage procedure that can be both costly and prolong the stay in hospital. Here, we present the case of a patient with deep burns to the plantar aspect of both feet. Given the patient's medical history of diabetes, hypertension and peripheral neuropathy, we elected to use IntegraTM in combination with negative pressure wound therapy. Three weeks after the application of the IntegraTM matrix, the surface layer was replaced with autograft. At discharge, the patient was fully ambulatory and six months post-operatively this status was maintained without significant graft breakdown. To the best of our knowledge, the use of IntegraTM and split thickness skin graft in the management of full thickness burns to the plantar aspect of the feet has not been reported previously. Overall, our experience with IntegraTM in this setting was found to be satisfactory and can be considered as a promising treatment option in acute burn resurfacing. Keywords: Burns, Dermal substitute, Integra™, Negative pressure wound therapy, Skin graft, Split thickness
url http://www.sciencedirect.com/science/article/pii/S2352587818300172
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