Current Approaches and Future Perspectives for Nanobodies in Stroke Diagnostic and Therapy

Antibody-based biologics are the corner stone of modern immunomodulatory therapy. Though highly effective in dampening systemic inflammatory processes, their large size and Fc-fragment mediated effects hamper crossing of the blood brain barrier (BBB). Nanobodies (Nbs) are single domain antibodies de...

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Bibliographic Details
Main Authors: Larissa Jank, Carolina Pinto-Espinoza, Yinghui Duan, Friedrich Koch-Nolte, Tim Magnus, Björn Rissiek
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Antibodies
Subjects:
Online Access:http://www.mdpi.com/2073-4468/8/1/5