Safety of red ginseng oil for single oral administration in Sprague–Dawley rats

The single oral administration of red ginseng oil (5000 mg/kg) to Sprague–Dawley rats induced no changes in behavioral patterns, clinical signs, and body weight, and hepatotoxicity parameters such as aspartate aminotransferase and alanine aminotransferase for 14 d. Therefore, these results suggest t...

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Main Authors: Min-Ji Bak, Kyu-Bong Kim, Mira Jun, Woo-Sik Jeong
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Ginseng Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845313000109
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spelling doaj-96ec54ab7bbf4326a5b7a861089e486d2020-11-24T23:32:24ZengElsevierJournal of Ginseng Research1226-84532014-01-01381788110.1016/j.jgr.2013.11.009Safety of red ginseng oil for single oral administration in Sprague–Dawley ratsMin-Ji Bak0Kyu-Bong Kim1Mira Jun2Woo-Sik Jeong3Department of Food and Life Sciences, College of Biomedical Science and Engineering, Inje University, Gimhae, KoreaDepartment of Pharmacy, College of Pharmacy, Dankook University, Cheon-An, KoreaDepartment of Food Science and Nutrition, Dong-A University, Busan, KoreaDepartment of Food and Life Sciences, College of Biomedical Science and Engineering, Inje University, Gimhae, KoreaThe single oral administration of red ginseng oil (5000 mg/kg) to Sprague–Dawley rats induced no changes in behavioral patterns, clinical signs, and body weight, and hepatotoxicity parameters such as aspartate aminotransferase and alanine aminotransferase for 14 d. Therefore, these results suggest that the red ginseng oil is safe and nontoxic acutely.http://www.sciencedirect.com/science/article/pii/S1226845313000109Panax ginsengred ginseng oilsafetysingle oral dose
collection DOAJ
language English
format Article
sources DOAJ
author Min-Ji Bak
Kyu-Bong Kim
Mira Jun
Woo-Sik Jeong
spellingShingle Min-Ji Bak
Kyu-Bong Kim
Mira Jun
Woo-Sik Jeong
Safety of red ginseng oil for single oral administration in Sprague–Dawley rats
Journal of Ginseng Research
Panax ginseng
red ginseng oil
safety
single oral dose
author_facet Min-Ji Bak
Kyu-Bong Kim
Mira Jun
Woo-Sik Jeong
author_sort Min-Ji Bak
title Safety of red ginseng oil for single oral administration in Sprague–Dawley rats
title_short Safety of red ginseng oil for single oral administration in Sprague–Dawley rats
title_full Safety of red ginseng oil for single oral administration in Sprague–Dawley rats
title_fullStr Safety of red ginseng oil for single oral administration in Sprague–Dawley rats
title_full_unstemmed Safety of red ginseng oil for single oral administration in Sprague–Dawley rats
title_sort safety of red ginseng oil for single oral administration in sprague–dawley rats
publisher Elsevier
series Journal of Ginseng Research
issn 1226-8453
publishDate 2014-01-01
description The single oral administration of red ginseng oil (5000 mg/kg) to Sprague–Dawley rats induced no changes in behavioral patterns, clinical signs, and body weight, and hepatotoxicity parameters such as aspartate aminotransferase and alanine aminotransferase for 14 d. Therefore, these results suggest that the red ginseng oil is safe and nontoxic acutely.
topic Panax ginseng
red ginseng oil
safety
single oral dose
url http://www.sciencedirect.com/science/article/pii/S1226845313000109
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AT woosikjeong safetyofredginsengoilforsingleoraladministrationinspraguedawleyrats
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