Fucoxanthin Enhances Cisplatin-Induced Cytotoxicity via NFκB-Mediated Pathway and Downregulates DNA Repair Gene Expression in Human Hepatoma HepG2 Cells

Cisplain, a platinum-containing anticancer drug, has been shown to enhance DNA repair and to inhibit cell apoptosis, leading to drug resistance. Thus, the combination of anticancer drugs with nutritional factors is a potential strategy for improving the efficacy of cisplatin chemotherapy. In this st...

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Bibliographic Details
Main Authors: Cheng-Ling Liu, Yun-Ping Lim, Miao-Lin Hu
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:Marine Drugs
Subjects:
B
Online Access:http://www.mdpi.com/1660-3397/11/1/50